What Your Prescriptions Cost
How much does Trulicity cost with Medicare in 2026?
Last reviewed: · Big Sioux Benefits Data Desk
Trulicity has no Medicare-negotiated price in 2026. CMS claims data shows Part D spent an average of $1,295.09 per Trulicity claim in 2025, across 582,333 beneficiaries and $4.8 billion in total spending, averaging $8,287.43 per beneficiary for the year. Under the standard 2026 benefit, a member filling it monthly reaches the $2,100 out-of-pocket cap around the sixth month.
The qualifier, and it is genuinely good news if you take this drug: on January 27, 2026, CMS selected Trulicity for the third cycle of Medicare drug price negotiation, with negotiated prices taking effect January 1, 2028. It was the largest drug on that selection list by Medicare expenditure, at $4.9 billion across Part B and Part D for November 2024 through October 2025, covering 617,000 enrollees.
Where Trulicity stands
| Question | Answer |
|---|---|
| Negotiated price in 2026? | No |
| Selected for negotiation? | Yes, announced January 27, 2026 |
| When a negotiated price takes effect | January 1, 2028 |
| Average Part D spending per claim, 2025 | $1,295.09 |
| Your approximate out-of-pocket for 2026 | $2,100, the cap, reached around month six |
How this illustration is built: the 2026 standard Part D benefit, meaning a full $615 deductible, then 25% coinsurance, then $0 once your out-of-pocket total reaches $2,100. Your plan may use copays instead of coinsurance, may charge a smaller deductible or none, and may place the drug on a different tier, so treat this as the shape of the year rather than a quote. We are not showing plan-specific copays because we will not publish a number we cannot source.
Practically, the 2028 date does not change your 2026 or 2027 budgeting, and the annual cap is doing the real work in the meantime: whatever the drug costs, your covered Part D spending stops at $2,100 a year. The full selection list for 2028 is in which drugs are next for Medicare negotiation.
Sources
- CMS — Medicare Part D Spending by Drug — CY2025 full year and CY2026 Q1 files; accessed 2026-08-21
- CMS — Medicare Drug Price Negotiation Program: Selected Drugs for Initial Price Applicability Year 2028 — announced January 27, 2026; accessed 2026-08-21
- CMS — Announcement of Calendar Year 2026 Medicare Advantage Capitation Rates and Part C and Part D Payment Policies (Part D benefit parameters) — CY2026 parameters; accessed 2026-08-21
Related questions
Should I switch off Trulicity because it is expensive?
That is a clinical decision for your prescriber, not a cost decision to make alone. What is worth raising with them is that the $2,100 annual cap limits your exposure regardless of the drug's price, so the cost argument for switching is weaker in 2026 than it was before the cap existed.
Will Trulicity get cheaper before 2028?
Its negotiated price is scheduled for January 1, 2028. Before then, its price could still move for other reasons, and your own cost could change if your plan alters its tier placement at a plan-year boundary. Nothing about the negotiation program lowers its price before 2028.
Drug costs turn on your specific prescriptions, so the arithmetic is worth doing once, properly: book a free, no-pressure conversation, see your county's South Dakota plan lineup, or browse all answers. SHIINE, the state's free counseling program, is at 1-800-536-8197 and sells nothing.
Big Sioux Benefits is a licensed insurance agency, not affiliated with or endorsed by the U.S. government or the federal Medicare program. We do not offer every plan available in your area. Contact Medicare.gov, 1-800-MEDICARE, or SHIINE (South Dakota's SHIP) for all of your options.